Searchable abstracts of presentations at key conferences in endocrinology

ea0016p61 | Adrenal | ECE2008

A case of renin-producing adrenocortical carcinoma with Cushing's syndrome: in vitro effect of serotonin on renin and cortisol secretions

Louiset Estelle , Isvi Karen , Gasc Jean-Marie , Duparc Celine , Cauliez Bruno , Laquerriere Annie , Kuhn Jean-Marc , Lefebvre Herve

A 48-year-old woman was referred for ACTH-independent Cushing’s syndrome associated with a left adrenal tumor. Contrasting with hypercortisolism-related hypertension and hypokalemia, renin and aldosterone levels were paradoxically increased. The tumor was surgically removed and pathological examination of the tissue established the diagnosis of corticosurrenaloma. Fragments of the tumor were obtained for in situ hybridization, immunohistochemical and cell incubatio...